E-ISSN 2149-2530
Original Article
The effect of Pulmonary Rehabilitation on the value of inspiratory capacity-to-total lung capacity (IC/TLC) ratio in patients with COPD
1 Department of Chest Diseases, Dr. Suat Seren Chest Diseases and Thoracic Surgery Training and Research Hospital, İzmir, Turkey  
2 Pulmonary Rehabilitation Unit, Dr. Suat Seren Chest Diseases and Thoracic Surgery Training and Research Hospital, İzmir, Turkey  
3 Department of Chest Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey  
Turk Thorac J ; 5: -
DOI: 10.5152/TurkThoracJ.2018.089
Key Words: COPD, IC/TLC, pulmonary rehabilitation, dyspnea
Abstract

OBJECTIVE: In patients with COPD, IC/TLC has been found to be correlated with mortality and reduced exercise capacity. Pulmonary rehabilitation (PR) is known to improve exercise capacity and respiratory functions of COPD patients. Our study aims to examine the impact of PR on IC/TLC ratio in patients with COPD.


MATERIALS AND METHODS
: We included a total of 122 patients with COPD, who received PR therapy twice a week over a period of 8 weeks in an outpatient clinic.


RESULTS
: Patients’ mean age was 62.5 (±8.2), 15 patients (12.3%) were female. Post-PR FEV1, TLCO, and pO2 values, and 6mWD, dyspnea, and quality of life scores indicated a statistically significant improvement (p<0.05 for all). Patients were grouped as follows: IC/TLC>0.25 as Group 1 and IC/TLC≤0.25 as Group 2. Both groups exhibited a significantly increased post-PR 6mWT distance (375-420, 336-400 m) with no difference between the groups. We observed significantly increased FEV1% in both groups after the PR (p=0.007, 0.004). Again, quality of life questionnaires and mMRC scores significantly improved for both groups (p<0.001). Although no post-PR IC/TLC improvement was detected in patients with good prognosis, we identified an IC/TLC improvement in the poor prognosis group (Group 2) (p=0.002).


CONCLUSION
: COPD patients with IC/TLC≤0.25 benefit from the PR just as those COPD patients with IC/TLC>0.25.


Cite this article as
: Varol Y, Şahin H, Aktürk Ü, et al. The effect of Pulmonary Rehabilitation on the value of inspiratory capacity-to-total lung capacity (IC/TLC) ratio in patients with COPD. Turk Thorac J 2018; DOI: 10.5152/TurkThoracJ.2018.089

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