E-ISSN 2149-2530
Case report
Association of Acromegaly and Central Sleep Apnea Syndrome
1 Department of Pulmonary Diseases, Gaziopsmanpaşa University School of Medicine, Tokat, Turkey  
2 Department of Pulmonary Diseases, Gaziosmanpaşa University School of Medicine, Tokat, Turkey  
3 Department of Internal Medicine, Gaziosmanpaşa University School of Medicine, Tokat, Turkey  
4 Department of Radiology, Gaziosmanpaşa University School of Medicine, Tokat, Turkey  
Turk Thorac J ; 5: -
DOI: 10.5152/TurkThoracJ.2017.17003
Key Words: Acromegaly, obstructive sleep apnea, polysomnography, growth hormone
Abstract

Acromegaly is usually characterized by the excessive secretion of growth hormone (GH) after the closure of epiphyseal plaques, resulting from functional pituitary adenomas. The most common manifestations of acromegaly are acral and soft tissue overgrowth, diabetes mellitus, hypertension, and heart and respiratory failure. In patients, obstruction of the upper airway may develop due to enlargement of the tongue and thickening of the tissues of the larynx; consequently, obstructive sleep apnea syndrome (OSAS) occurs commonly in acromegaly. Previous studies have shown an association between acromegaly and central sleep apnea syndrome (CSAS). Some of these described patients described showed that an elevation in the GH level may cause a defect in the respiratory drive. Most systemic diseases seen in acromegaly require effective treatment. We believe that it is necessary to perform effective treatments by examining respiratory disorders in sleep.

Cite this article as: Pazarlı AC, Köseoğlu Hİ, Kutlutürk F, et al. Association of Acromegaly and Central Sleep Apnea Syndrome. Turk Thorac J 2017. DOI: 10.5152/TurkThoracJ.2017.17003

Key Words
Authors
All
Author's Corner
Survey
AVES | Copyright © 2018 Turkish Thoracic Society Latest Update: 12.04.2018