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Lipoma is a benign neoplasm composed of adult adipose tissue and occasionally fibrous stroma. Lipomas originating from the pleura are very rare. It is possible to make a diagnosis of lipoma preoperatively by computed tomography (CT) and magnetic resonance imaging (MRI). Definitive diagnosis is made at CT with occasionally lesions have fat attenuation (approximately -100 HU). MRI may also be useful to better characterize these lesions. We report radiological findings an unusual case of bilateral lipoma in a 70-year-old female that presented as a pleural-based mass. The present case represents the only example of this bilateral entity.