Thoracic Research and Practice
Clinical Study

Bronchiectasis: A Sign of Chronic Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation

1.

Department of Thoracic Surgery, Marmara University Hospital, İstanbul, Turkey

Thorac Res Pract 2000; 1: Turkish Respiratory Journal 26-27
Read: 436 Downloads: 331 Published: 06 October 2021

A 19-year-old man is reported who had underwent bone marrow transplantation (BMT) for acute myelogenous leukemia developed respiratory complaints of productive cough and progressive dyspnea at post-transplant day 278 and was hospitalised. Chest-x-ray and high resolution computed tomogaphy (HRCT) revealed cylindirical bronchiectasis. Pathologic examination of transbronchial biopsy was consistent with chronic graft-versus-host disease(CGVHD). The patient had no history of respiratoiy disease or any other condition that could cause bronchiectasis other than CGVHD. Bronchiectasis can be considered as an early predictor of CGVHD and its early diagnosis by HRCT in suspicion of GVHD after BMT may lead to early re-evaluation of treatment.

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EISSN 2979-9139