Thoracic Research and Practice
Original Article

Diagnostic Value of Early Reversibility Test


Sultan 1. İzzettin Keykavus Devlet Hastanesi, Göğüs Hastalıkları Kliniği, Sivas, Türkiye


Cumhuriyet Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Sivas, Türkiye

Thorac Res Pract 2006; 7: Toraks Dergisi 178-182
Read: 1041 Downloads: 836 Published: 18 July 2019


In the early reversibility test, spirometry is repeated to assess the bronchodilatation following the administration of an aerosol bronchodilator. It is unique spirometric test for the differential diagnosis between asthma and chronic obstructive pulmonary disease (COPD). Forced vital capacity (FVC) and forced expiratory volume in 1st second (FEV1) before and 20 minutes after inhalation of 200 microgram salbutamol were retrospectively analyzed in patients of asthma (n=65) and COPD (n=71). FVC-related parameters had no a significant effects in the differential diagnosis. No significant correlations were observed between the increase in FEV1 and age or smoking history. The best parameter in the differential diagnosis of asthma and COPD was the percentage of the increase in FEV1 / predicted FEV1, and with a cut-off level for 6.5 %, the sensitivity and the specificity were only 81 %, and 86 %, respectively. In conclusions, acute bronchodilator response has a limited value in differentiating bronchial asthma from COPD.

EISSN 2979-9139