Thoracic Research and Practice
ORIGINAL INVESTIGATIONS

Evaluation of Malignant Mesothelioma Patients: A Ten Years' Experience

1.

SSK Süreyyapaşa Hospital for Chest Disease and Thoracic Surgery, Department of Pulmonology, Istanbul, Turkey

2.

Department of Chest Diseases, Karaelmas University Faculty of Medicine, Zonguldak, Turkey

3.

SSK Süreyyapaşa Center for Chest Disease and Thoracic Surgery, Istanbul, Turkey

4.

SSK Süreyyapaşa Chest, Thoracic and Cardiovascular Diseases Hospital, 5. Clinic, İstanbul, Turkey

5.

SSK Süreyyapaşa Center for Chest Diseases and Thoracic Surgery, Istanbul-Turkey

Thorac Res Pract 2005; 6: Turkish Respiratory Journal 149-152
Read: 457 Downloads: 260 Published: 12 October 2021

We reviewed malignant pleural mesothelioma (MPM) cases diagno­sed at our hospital between 1993 and 2002 with respect to age, sex, histologic type, diagnostic method, stage, and history of occupati­onal and environmental asbestos exposure. Of 106 patients aged bet­ween 31 and 83 years (mean age 54.75 years), 28 patients (26%) we­re females and 78 (74%) were males. Ninety-one patients (84%) had asbestos exposure, which was found to be occupational in 14 pati­ents (13%), environmental in 41 patients (39%) and both occupa­tional and environmental in 36 (34%). In 15 patients (14%) no as­bestos exposure was reported. Fifty-two patients (49%) were afflicted with the epithelial, 18 (17%) with the mixed, and one patient (1%) with the sarcomatous subtype of MPM. In 35 patients (33%) the his­tologic subtype was not clear. Diagnosis was confirmed by biopsy alo­ne in 43 patients (42%), by cytology alone in 5 patients (5%), by open lung biopsy in 53 (50%), by transthoracic needle aspiration bi­opsy in 3(2%), by skin biopsy in one patient (1%) and by mediasti- notomy in one patient (1%). The majority (76%) of the patients were advanced cases at presentation. Distribution of 106 patients ac­cording to tumor stages I,II,III and IV were 9%, 15%, 54%, and 22% respectively. Pleural effusion was present in 75 patients (71%). En­vironmental asbestos exposure rather than occupational exposure was found to be (73% vs. 47%) a major determinant in the etiology of MPM in this group of Turkish patients.

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