Thoracic Research and Practice
Case report

False Positivity and False Negativity on Positron Emission Tomography in a Patient with Lung Cancer

1.

Department of Chest Diseases, Faculty of Medicine, Ufuk University, Ankara, Turkey

2.

Department of Urology, Faculty of Medicine, Ufuk University, Ankara, Turkey

3.

Department of Nuclear Medicine, Faculty of Medicine, Ufuk University, Ankara, Turkey

Thorac Res Pract 2012; 13: 174-177
DOI: 10.5152/ttd.2012.36
Read: 1338 Downloads: 965 Published: 18 July 2019

Abstract

Lung cancer is the leading cause of cancer-related deaths worldwide and non-small cell lung cancer (NSCLC) accounts for about 85% of the cases. Since its introduction in 2001, positron emission tomography (PET-CT) has been used in early diagnosis, staging, early and accurate detection of recurrences. In this report, we wish to present a case of lung cancer who was upstaged after thoracotomy and lymph node dissection despite a first evaluation with PET-BT and also, during follow up, the patient was misdiagnosed as a recurrence due to false positive uptake on PET-BT. Interestingly, the patient also had a synchronous testicular tumor which was not smoking-related. In this case, the false positive and false negative results of PET-BT was seen in the same patient. Additionally, the patient had a seminoma accompanying the lung cancer, which was not reported previously. Clinicians who deals with management of lung cancer should keep in mind that PET-BT may cause false positive and false negative results, so histopathological confirmation is necessary, and multiple independent primary tumors may accompany to lung cancer, even non-tobacco related ones, but it does not seem to be effective in the prognosis of the patient. (Turk Toraks Derg 2012; 13: 174-7)

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