Thoracic Research and Practice
Original Article

Initial COVID-19 Severity and Long-COVID Manifestations: An Observational Analysis

1.

Department of Pulmonary Medicine, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

2.

Department of Microbiology, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

3.

Department of Virology, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

4.

Department of Biostatistics, Viswanathan Chest Hospital, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India

Thorac Res Pract 2023; 24: 22-28
DOI: 10.5152/ThoracResPract.2023.21307
Read: 36 Downloads: 25 Published: 01 January 2023

OBJECTIVE: New-onset or persistent symptoms beyond after 4 weeks from COVID-19 are termed “long-COVID.” Whether the initial severity of COVID-19 has a bearing on the clinicoradiological manifestations of long COVID is an area of interest.

MATERIAL AND METHODS: We did an observational analysis of the long-COVID patients after categorizing them based on their course of COVID-19 illness into mild, moderate, and severe groups. The clinical and radiological profile was compared across these groups.

RESULTS: Out of 150 long-COVID patients recruited in the study, about 79% (118), 14% (22), and 7% (10) had a history of mild, moderate, and severe COVID-19, respectively. Fatigue (P = .001), breathlessness (P = .001), tachycardia (P = .002), tachypnea (P < .001), raised blood pressure (P < .001), crepitations (P = .04), hypoxia at rest (P < .001), significant desaturation in 6-minute walk test (P = .27), type 1 respiratory failure (P = .001), and type 2 respiratory failure (P = .001) were found to be significantly higher in the long-COVID patients with a history of severe COVID-19. These patients also had the highest prevalence of abnormal chest X-ray (60%) and honeycombing in computed tomography scan thorax (25%, P = .027).

CONCLUSION: The course of long COVID bears a relationship with initial COVID-19 severity. Patients with severe COVID-19 are prone to develop more serious long-COVID manifestations.

Cite this article as: Goel N, Goyal N, Spalgais S, et al. Initial COVID-19 severity and long-COVID manifestations: an observational analysis.Thorac Res Pract. 2023;24(1):22-28.

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