Thoracic Research and Practice
Case report

Montelukast and Churg-Strauss Syndrome

1.

Department of Chest Diseases, Dicle University School of Medicine, Diyarbakır, Turkey

2.

Clinic of Pulmonary Medicine, Memorial Dicle Hospital, Diyarbakir, Turkey

3.

Dicle University Faculty of Medicine, Department of Chest Diseases, Diyarbakır, Turkey

4.

Dicle University Faculty of Medicine, Department of Cardiology, Diyarbakır, Turkey

5.

Dicle University Faculty of Medicine, Department of Ear, Nose, Throat, Diyarbakır, Turkey

6.

Dicle University Faculty of Medicine, Department of Pathology, Diyarbakır, Turkey

Thorac Res Pract 2007; 8: Turkish Respiratory Journal 27-29
Read: 522 Downloads: 312 Published: 14 October 2021

A 37-year-old asthmatic presented with arthralgia, dyspnea, hemo­ptysis, wheezing, abdominal pain, and eosinophilia. He did not re­ceive any corticosteroid therapy previously and five weeks prior to admission Montelukast was started. Transthoracic echocardiography showed severely depressed left ventricular function with an ejection fraction of 20-25%. By the diagnosis of Montelukast-assoclated Churg- Strauss syndrome with cardiac involvement, the drug was stopped and steroids started. During the follow up period of 3 years, he did not have an other vasculitic episode. Although this is a rare association, the clinicians need to be vigilant in all patients who develop systemic symptoms when starting treatment with leukotriene antagonists.

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EISSN 2979-9139