Abstract

Invasive pulmonary aspergillosis is one of the serious complications in neutropenic patients with malignancy. The frequency of aspergillosis in these patients is related to the severity and duration of neutropenia, conditions causing the increased number of spores in the environment (insulation at the hospital, decaying vegetation) and/or T lymphocyte deficiency or dysfunction. In this paper, we report four cases of invasive pulmonary aspergillosis in patients with leukemia, which were diagnosed simultaneously and resolved after liposomal amphotericin B treatment.