Thoracic Research and Practice
Clinical Study

Sister-chromatid Exchange Frequency in Women Who Exposed to Biomass in a Village of Central Anatolia

1.

Department of Medical Biology and Genetics, Faculty of Medicine, Cumhuriyet University, 58140 Sivas, Turkey

2.

Department of Biostatistics, Faculty of Medicine, Cumhuriyet University, 58140 Sivas, Turkey

3.

Department of Chest Diseases, Faculty of Medicine, Cumhuriyet University, 58140 Sivas, Turkey

Thorac Res Pract 2001; 2: Turkish Respiratory Journal 26-28
Read: 466 Downloads: 274 Published: 07 October 2021

Objective: Biomass fuels are used by most of the people living in the rural areas (wood, agricultural waste and dung are used by about half of the world population) as a major, and most of the time as the only source of domestic energy for cooking and heat­ing. Sister-Chromatid Exchange (SCE) values are analyzed in our study, to determine the mutagenic effects of exposure to biomass fuels.

Design and Patients: Sister-chromatid exchange analysis has been performed on peripheral lymphocytes by conventional sito- genetics method. In this study, two groups as 20 non-smoker sub­jects who are healthy women between 25 and 70 years of age, and have exposed to biomass for ten years, 3-5 hours per day, and 20 healthy women at the same age who did not exposed to biomass fuels were evaluated.

Measurements and Results: The mean SCE frequency was increased significantly in the study group in contrast to the con­trol group in statistical evaluation, which is applied by the Man- Whitney U- test (p<0.05).

Conclusion: We suggest that, our findings support a transient increase in SCE after exposure to biomass fuels and there are con­stant and harmful effects of biomass fuels on increased SCE fre­quency.

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EISSN 2979-9139