Thoracic Research and Practice
ORIGINAL INVESTIGATIONS

Survival and Prognostic Factors in Resected cN2-pN2 Non-Small-Cell Lung Cancer

1.

Surgical Oncology, Division of Cancer Medicine, Hokkaido University Graduate School of Medicine, Kita 14, Nishi 5, Kita-leu, Sapporo, Hokkaido 060-8638, Japan

Thorac Res Pract 2004; 5: Turkish Respiratory Journal 154-158
Read: 502 Downloads: 289 Published: 11 October 2021

The aims of this study were to reveal the prognostic factors of cN2- pN2 and to define the criteria to select appropriate surgical candi­dates.From 1982 to 1997, 40 patients with cN2 were operated on, who actually had pN2. We retrospectively analyzed the survival of the­se 40 patients by means of a univariate and multivariate analysis. The overall 5-year survival rate of the cN2-pN2 patients was 21%. According to multivariate analysis, single metastatic MLN station, absence of parietal pleural involvement and low CEA level impro­ved the prognosis. The 5-year survival rate of the patients with all of the three prognostic factors (n=6) was 67% and that of those with two prognostic factors (n=9) was 21%, compared with 0% in those with one or none (n=24) (p<0.01 and p=0.05, respectively). Even in cN2-pN2, patients with these three prognostic factors can benefit from primary surgical treatment, and can have long-term survival.

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