Thoracic Research and Practice
Original Article

The Effect of Biomass Exposure on Lipid Peroxidation and Antioxidant Enzyme Activities in Turkish Female Groups in Rural Areas

1.

Cumhuriyet ÜTF Göğüs Hast. Anabilim Dalı

2.

CÜTF Biyokimya Anabilim Dalı

3.

Cumhuriyet Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Sivas, Türkiye

4.

Cumhuriyet Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Allerjik Hastalıklar Bilim Dalı, Sivas, Türkiye

Thorac Res Pract 2000; 1: Toraks Dergisi 13-18
Read: 1096 Downloads: 818 Published: 18 July 2019

Abstract

The purpose of this study is to examine the change in lipid peroxidation and antioxidant enzyme activities due to biomass exposure. The group1 includes 30 non-smoker females that have not exposed to biomass. The group2 includes 34 smoker females but have not exposed to any kind of biomass. The group-3 includes 36 non-smoker females. The females in this group were exposed to indoor pollution. Erytrocite malondialdehid (EMDA) and plasma malondialdehid (PMDA) activities of these groups were analyzed as an indicator of the lipid peroxidation activities. Moreover, the blood ferritin (BF) levels of cases were measured. Superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) activities were measured as an indicator of antioxidant activities. EMDA, PMDA, and BF levels of group-2 and 3 was much higher than group-1 (p<0.05). There was no significant difference in BF level of group-2 and 3 (p>0.05) whereas PMDA level was much higher in group-2 compared to group-3. The SOD, GSH-Px, and CAT levels of group-2 and 3 was much lower than group-1 (p<0.05). There was no statistically significant difference between GSH-Px and CAT levels of group-2 and 3. In conclusion, there was a significant increase in lipid peroxidation activity and a significant decrease in antioxidant enzyme activity in female groups who were exposed to indoor pollution. Furthermore, it has been observed that these effects were higher for smoker females than that of nonsmokers.

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EISSN 2979-9139