Turkish Thoracic Journal
Original Article

The Relationship between Serum Endocan Levels and Childhood Community-acquired Pneumonia


Department of Pediatrics, Division of Pediatric Pulmonology Erciyes University School of Medicine, Kayseri, Turkey


Department of Biochemistry Erciyes University School of Medicine, Kayseri, Turkey

Turk Thorac J 2020; 21: 3-7
DOI: 10.5152/TurkThoracJ.2019.180105
Read: 240 Downloads: 169 Published: 02 September 2019

Objective: Community-acquired pneumonia is a potentially lethal lower respiratory tract infection for children. For this reason, it is important to recognize the disease early and to treat it appropriately and also we need to determine which patient will be hospitalized or not hospitalized. We aimed to evaluate plasma endocan level for determining the whether is it effective in giving the decision of hospitalization and the assessment of the response to treatment in patients with CAP.

Material and Methods: This prospective case-control study was conducted between November 2015 and May 2016 at Erciyes University School of Medicine. Fifty-three patients, who were diagnosed with CAP with clinical and radiological findings. The patients were divided into various subgroups such as inpatient, outpatient, complicated, no-complicated, and dead patients etc. and the levels of endocan were compared between the control group and their own.

Results: Total 53 children with a diagnosis of CAP and 55 healthy children were enrolled in the study. Patients were divided into two groups: hospitalized patients and outpatient groups. There was no statistically significant difference between these groups' serum endocan levels on the first day and serum endocan levels on the fourth day (p=0.783, p=0.419)

Conclusion: Serum endocan level had no significant value in determining patients' hospitalization. On the other hand, high serum endocrine levels may be significant in determining the severity of the disease and poor prognosis

Cite this article as: Hangül M, Öztürk D, Barlak Keti D, et al. Relationship between Serum Endocan Levels and Childhood Community-Acquired Pneumonia. Turk Thorac J 2020; 21(1): 3-7.

EISSN 2149-2530