Turkish Thoracic Journal
Original Article

The Role of Pneumococcal Pneumonia among Community-Acquired Pneumonia in Adult Turkish Population: TurkCAP Study

1.

Department of Infectious Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey

2.

Department of Pulmonary Diseases, Akdeniz University, Faculty of Medicine, Antalya, Turkey

3.

Department of Pulmonary Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey

4.

Department of Infectious Diseases and Clinical Microbiology, 18 Mart University, Faculty of Medicine, Çanakkale, Turkey

5.

Department of Pulmonary Diseases, Dicle University, Faculty of Medicine, Diyarbakır, Turkey

6.

Department of Infectious Diseases and Clinical Microbiology, Mardin State Hospital, Mardin, Turkey

7.

Department of Infectious Diseases and Clinical Microbiology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey

8.

Department of Emergency Medicine, Ankara Atatürk Training and Research Hospital, Ankara, Turkey

9.

Department of Infectious Diseases, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey

10.

Department of Pulmonary Diseases, Gazi University, Faculty of Medicine, Ankara, Turkey

11.

Department of Infectious Diseases and Clinical Microbiology, Hitit University, Faculty of Medicine, Çorum, Turkey

12.

Department of Pulmonary Diseases, Yüzüncü Yıl University, Faculty of Medicine, Van, Turkey

13.

Department of Pulmonary Diseases, Adnan Menderes University, Faculty of Medicine, Aydın, Turkey

14.

Department of Infectious Diseases and Clinical Microbiology, Bozok University, Faculty of Medicine, Yozgat, Turkey

15.

Department of Pulmonary Diseases, Dokuz Eylül University, Faculty of Medicine, Izmir, Turkey

16.

Department of Pulmonary Diseases, Ege University, Faculty of Medicine, Izmir, Turkey

17.

Department of Infectious Diseases and Clinical Microbiology, Erzurum Regional Training and Research Hospital, Erzurum, Turkey

18.

Department of Pulmonary Diseases and Sleep Disorder, Acıbadem Health Group Maslak Hospital, Istanbul, Turkey

19.

Department of Infectious Diseases and Clinical Microbiology, Acıbadem Health Group Maslak Hospital, Istanbul, Turkey

20.

Department of Infectious Diseases and Clinical Microbiology, Başkent University Konya Hospital, Konya, Turkey

21.

Department of Pulmonary Diseases, Sutcu Imam University, Faculty of Medicine, Kahramanmaraş, Turkey

22.

Department of Infectious Diseases, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey

23.

Department of Pulmonary Diseases, Ankara Atatürk Training and Research Hospital, Ankara, Turkey

Turk Thorac J 2021; 22: 339-345
Read: 122 Downloads: 21 Published: 09 July 2021

Objective: To evaluate the rate of pneumococcal pneumonia (PP) among patients with community-acquired pneumonia (CAP) in Turkey and to investigate and compare features of PP and non-PP CAP patients.

Material and Methods: This multicenter, non-interventional, prospective, observational study included adult CAP patients (age ≥ 18 years). Diagnosis of PP was based on the presence of at least 1 positive laboratory test result for Streptococcus pneumoniae (blood culture or sputum culture or urinary antigen test [UAT]) in patients with radiographic findings of pneumonia.

Results: Four hundred sixty-five patients were diagnosed with CAP, of whom 59 (12.7%) had PP. The most common comorbidity was chronic obstructive pulmonary disease (30.1%). The mean age, smoking history, presence of chronic neurological disease, and CURB-65 score were significantly higher in PP patients, when compared to non-PP patients. In PP patients, 84.8% were diagnosed based ony on the UAT. The overall rate of PP patients among CAP was calculated as 22.8% considering the UAT sensitivity ratio of 63% (95% confidence interval: 45-81). The rate of intensive care treatment was higher in PP patients (P = .007). While no PP patients were vaccinated for pneumococcus, 3.8% of the non-PP patients were vaccinated (P = .235). Antibiotic use in the preceding 48 hours was higher in the non-PP group than in the PP group (31.8% vs. 11.1%, P = .002). The CURB-65 score and the rate of patients requiring inpatient treatment according to this score were higher in the PP group.

Conclusion: The facts that PP patients were older and required intensive care treatment more frequently as compared to non-PP patients underline the burden of PP.

Cite this article as: Şenol E, Çilli A, Günen H, et al. The role of pneumococcal pneumonia among community-acquired pneumonia in adult turkish population: TurkCap study. Turk Thorac J. 2021; 22(4): 339-345.224

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