E-ISSN 2149-2530
Original Article
Vitamin D Deficiency and Radiologic Findings in Adult Non-Cystic Fibrosis Bronchiectasis
1 Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Department of Chest Diseases, Istanbul, Turkey  
2 Giresun Dr. Ali Menekşe Chest Diseases Hospital, Department of Chest Diseases, Giresun, Turkey  
Turk Thorac J ; 5: -
DOI: 10.5152/TurkThoracJ.2019.18139
Key Words: Bronchiectasis, Bronchiectasis severity index, Radiology, Reiff's score, vitamin D deficiency
Abstract

Objective: Vitamin D may play important role in immunity and vitamin D deficiency has been related to increased respiratory infections. The aim of this study to detect prevalence of vitamin D deficiency and to investigate relationship between radiologic and clinical effects on adult bronchiectasis(BR) patients.

 

Material and Methods: A 130 patients with BR and 73 healthy people as a control group were enrolled to the study. Radiological severity was assessed using Modified Reiff Score.

 

Results: The mean age of patients was 41.9±9.1(Range 18-85). The mean 25(OH)D level of BR patients was 14.7±9.6 ng/ml and 19.8±6.9 ng/ml in control group (p=0.001). We found that 95(73.1%) of adult BR patients would be categorized as vitamin D deficient. Patients with vitamin D deficiency group were significantly higher mMRC scores than those in the group without vitamin D deficiency (p=0.036) The mean modified reiff score was higher in vitamin D deficient group than normal serum level 25(OH)D BR group(6.9±3.8 vs 4.9± 2.7, p=0.001). Forced vital capacity% predicted value was lower in the vitamin D deficient group too(p=0.02). This model showed that reiff score(OR 1.285(1.039-1.590), p=0.021) was independently related to vitamin D deficiency

 

Conclusion: We found that vitamin D deficiency is commonly seen in adult BR patients in a stable period. Likewise, It might be related to severe radiological findings on chest CT and worse lung functions.

 

Cite this article as: Niksarlıoğlu EY, Kılıç L, Bilici D, et al. Vitamin D Deficiency and Radiologic Findings in Adult Non-Cystic Fibrosis Bronchiectasis. Turk Thorac J 2019; DOI: 10.5152/TurkThoracJ.2019.18100

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