E-ISSN 2149-2530
Original Article
Carbon Monoxide in the Expired Air and Urinary Cotinine Levels of e-Cigarette Users
1 Department of Public Health, Hacettepe University School of Medicine, Ankara, Turkey  
2 Department of Pharmaceutical Toxicology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey  
3 Department of Preventive Oncology, Hacettepe University Cancer Institute, Ankara, Turkey  
Turk Thorac J 2019; 20: 125-129
DOI: 10.5152/TurkThoracJ.2018.18110
Key Words: Carbon monoxide, electronic cigarette, urinary cotinine

OBJECTIVES: The aim of this descriptive study was to determine the sociodemographic characteristics of electronic (e)-cigarette users for clarifying the causes of e-cigarette smoking and to identify the carbon monoxide (CO) and urinary cotinine levels of the volunteers.


MATERIALS AND METHODS: Twenty volunteers who smoked e-cigarettes completed a questionnaire, and their exhaled CO and urinary cotinine levels were measured. An enzyme-linked immunosorbent assay kit was used for cotinine analysis.


RESULTS: Overall, 85% of the participants were males, 60% were married, and 75% were college/university graduates. The median age of participants was 38.5 years. The participants' main reasons for starting to smoke were peer influence and curiosity. The participants’ main reasons for smoking e-cigarettes were to quit and reduce smoking the conventional cigarettes and cost effectiveness. Only three people knew that smoking was harmful to health. The participants' CO levels were measured as a median of 3, lowest of 1, and highest of 22. Cotinine levels were “positive” in all samples. A moderate and statistically significant correlation was found between the amount of fluids used by the participants in 1 day (mL) and cotinine levels in urine specimens (Pearson correlation test, r=0.511, p=0.025).


CONCLUSION: The study is an important proof of the country's scientific work on e-cigarettes. Preventive strategies should be very strictly implemented for any tobacco products, including e-cigarettes, as they harm individuals and the community.


Cite this article as: Aslan D, Gürbay A, Hayran M, et al. Carbon Monoxide in the Expired Air and Urinary Cotinine Levels of e-Cigarette Users. Turk Thorac J 2019; 20(2): 125-9.

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