E-ISSN 2149-2530
Original Article
Evaluation of subclinical atherosclerosis with carotid intima media and epicardial fat thickness in patients with sarcoidosis
1 Department of Pulmonary Medicine, Baskent University Faculty of Medicine, Adana, Turkey  
2 Department of Cardiology, Baskent University Faculty of Medicine, Adana, Turkey  
3 Department of Pulmonary Medicine, Baskent University Faculty of Medicine, Ankara, Turkey  
Turk Thorac J ; 5: -
DOI: 10.5152/TurkThoracJ.2019.19017
Key Words: Sarcoidosis, carotid intima media thickness, epicardial fat thickness , atherosclerosis
Abstract

Objective: Since many similar mechanisms may play a role in the pathophysiology of sarcoidosis and atherosclerosis, the risk of subclinical atherosclerosis may be increased in patients with sarcoidosis. The aim of this study was to evaluate the known markers of subclinical atherosclerosis of epicardial fat and carotid intima media thickness in patients with sarcoidosis.

 

Methods: This cross-sectional study included a total of 183 subjects, comprising 94 patients with sarcoidosis and a control group of 89 healthy individuals. Measurements were taken of epicardial fat and carotid intima media thickness from all subjects and recorded. The groups were compared and differences were analysed statistically.

 

Results: Epicardial fat thickness was higher in the patients than in the control subjects (6.42±1.12 vs. 7.13±1.41, p < 0.001). Carotid intima media thickness was higher in the patients than in the control subjects (0.51±0.02 vs. 0.52±0.02, p =0.003).

 

Conclusion: Epicardial fat and carotid intima media thickness values in patients with sarcoidosis were found to be increased compared to the control group. According to these results, the risk of subclinical atherosclerosis might be increased in these patients.

 

Cite this article as: Bozkurt Yılmaz HE, Yılmaz M, Erol T, et al. Evaluation of subclinical atherosclerosis with carotid intima media and epicardial fat thickness in patients with sarcoidosis. Turk Thorac J 2019; DOI: 10.5152/TurkThoracJ.2019.19017

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