E-ISSN 2149-2530
Original Article
Risk factors and clinical determinants in bronchiolitis
1 Necmettin Erbakan University Meram Faculty of Medicine, Department of Pediatrics, Division of Pediatric Pulmonology, Konya, Turkey  
2 Baskent University Konya Hospital, Department of Pediatrics, Division of Pediatric Allergy and Immunology, Konya, Turkey  
3 Necmettin Erbakan University Meram Faculty of Medicine, Department of Microbiology, Konya, Turkey  
Turk Thorac J ; 5: -
DOI: 10.5152/TurkThoracJ.2019.180168
Key Words: Viruses, bronchiolitis, infancy, asthma
Abstract

Objective: Our primary aim was to demonstrate the viral pathogens, clinical symptoms and findings of acute viral bronchiolitis attacks of child patients aged between 2 months and 2 years. Our secondary aim was to evaluate the clinical follow-up prognoses and detect the risk factors for recurrence and severity of bronchiolitis among them.

 

Material and Methods: Our study covered 101 children aged between 2 months and 2 years who had been diagnosed with clinical bronchiolitis between September 2011 and April 2012. The demographic, clinical, laboratory and radiological results of the cases were recorded. Nasopharyngeal swab samples were collected from the patients for virus studies and analyzed through polymerase chain reaction (PCR) method. Within the framework of at least one-year follow-ups with the patients, new attacks, existence of wheezing, frequency of pulmonary infections and progression of asthma were evaluated.

 

Results: In 50 of the 101 patients (49.5%), determinants were indicated through the PCR method, with the most frequent being respirarory syncytial virus (RSV) (44%). The frequency of bronchiolitis was higher in premature patients (p < 0.005). There was a significant relationship between crowded family structure and the existence of wheezing (p = 0.003), increased bronchiolitis recurrence (p = 0.014) and increased need for inhaler treatment (p = 0.014). The frequency of bronchiolitis was significantly higher in patients living in urban cities (p < 0.001), patients using heating stoves (p = 0.001) and patients living in houses with smokers (p = 0.001). Patients living in houses with heating stoves had more severe attacks than patients with central heating (p = 0.018). The asthma predictive index (API) levels of the wheezing patients in their follow-ups were found to be statistically significant (p = 0.008).

 

Conclusion: Prematurity, exposure to smoking, heating with stoves in a crowded house, and urban life are listed among the risk factors for frequent bronchiolitis. The API can be used to predict the recurrence of bronchiolitis.

 

Cite this article as: Atay Ö, Pekcan S, Göktürk B, et al. Risk factors and clinical determinants in bronchiolitis. Turk Thorac J 2019; DOI: 10.5152/TurkThoracJ.2019.180168

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